Jump to main content nature. vision loss from viagra Com homepage publications a-z index browse by subject my account submit manuscript register subscribe login cart search advanced search oncogene journal home > archive > original papers > full text > figures and tables figures and tables from: plasminogen activator inhibitor-1 (pai-1) modifies the formation of aggressive fibromatosis (desmoid tumor) catherine fen li, christopher kandel, frank baliko, puviindran nadesan, nils brünner and benjamin a alman back to article figure 1. (a) expression of pai-1 and gapdh is increased in aggressive fibromatosis (tumor) compared to normal fascial tissues (normal) from six patients. order viagra online Semiquantitative rt−pcr results are shown. viagra online The mean values95% confidence interval of the pai-1 intensity relative to gapdh expression were 1. 20. 2 and 0. viagra no prescription 30. 1 in aggressive fibromatosis and normal fascial tissues, respectively (p<0. 05). viagra samples (b, c) pai-1 immunostaining in paraffin-embedded section of human aggressive fibromatosis and surrounding normal tissue, showing more intense staining of a greater proportion of cells in the aggressive fibromatosis tumor (b) than that in the surrounding normal tissue on the same slide section (c) ( four hundred) full figure and legend (338k) figure 2. (a). Pai-1 promoter construct (p800-neo-luc) activity in nih3t3 cells. Activity of the reporter construct after induction of expression of the mutant stabilized -catenin or without induction of -catenin expression, and under the condition of incubation with either carrier or tgf-. vision loss from viagra The luciferase activity, after normalization to -gal activity95% confidence intervals is shown. Each experiment was performed in triplicate. There was no significance difference in pai-1 promoter activity with expression of the stabilized -catenin. first time viagra user Expression of the stabilized -catenin did result in a fourfold increase in tcf reporter activity compared to control. generic viagra online (b) pai-1 expression is tgf- dependent. Pai-1 expression, as detected using semiquantitative rt−pcr, was increased in the cell culture after induction of expression of the mutant stabilized -catenin. viagra generic This increase was blocked by the addition of a tgf- neutralizing antibody. vision loss from viagra -catenin protein level was elevated twofold by induction of the transgene (as previously reported in cheon et al. , 2002) full figure and legend (62k) figure 3. imdur 30 mg viagra Pai-1 deficiency reduced the number of aggressive fibromatosis tumors formed in male, but not female, apc/apc1638n mice. The number of aggressive fibromatoses per mouse95% confidence in apc/apc1638n;pai-1-/- and apc/apc1638n;pai-1+/+ littermates at 6 months of age is shown. There are 10 mice in each group.